Micromechanical models for the Brownian motion of hair cell stereocilia.
نویسندگان
چکیده
Brownian motion of the hairs (stereocilia) of amphibian hair cells has been shown in experiments to be in the range of some nm. Our models of the Brownian motion of coupled harmonic oscillators with mechanical properties of stereocilia lead to similar displacements. Computer simulation shows that stochastic fluctuations enhance the encoding of low level acoustic signals. Stochastic resonance lowers the detection threshold of auditory signals to amplitudes one order of magnitude lower than that of the Brownian motion.
منابع مشابه
Pure tone overstimulation changes the micromechanical properties of the inner hair cell stereocilia.
The effect of permanent noise-induced hearing loss on the auditory brainstem response (ABR) and the micromechanical properties of cochlear hair cell stereocilia in guinea pigs was investigated. The threshold of movement of the stereocilia was measured by applying force from a fluid filled pipette. After exposure to a 1.0 kHz pure tone signal at 105 dB(A) for 72 h the threshold of the ABR was br...
متن کاملThe effect of various conductivity and viscosity models considering Brownian motion on nanofluids mixed convection flow and heat transfer
In this paper the effect of using various models for conductivity and viscosity considering Brownian motion of nanoparticles is investigated. This study is numerically conducted inside a cavity full of Water-Al2O3 nanofluid at the case of mixed convection heat transfer. The effect of some parameters such as the nanoparticle volume fraction, Rayleigh, Richardson and Reynolds numbers has been ex...
متن کاملCochlear micromechanics - - A transduction physical model of
One of the basic questions which as persisted in the field of heating theory is the still unresolved mechanical action of hair-cell transduction. The fundamental problem that has historically plagued researches is the discrepancy between mechanically measured tuning of basilar membrane motion and neurally measured tuning. Inthis paper we show that he difference between these two measures appear...
متن کاملSliding adhesion confers coherent motion to hair cell stereocilia and parallel gating to transduction channels.
When the tip of a hair bundle is deflected by a sensory stimulus, the stereocilia pivot as a unit, producing a shearing displacement between adjacent tips. It is not clear how stereocilia can stick together laterally but still shear. We used dissociated hair cells from the bullfrog saccule and high-speed video imaging to characterize this sliding adhesion. Movement of individual stereocilia was...
متن کاملLive-cell imaging of actin dynamics reveals mechanisms of stereocilia length regulation in the inner ear
The maintenance of sensory hair cell stereocilia is critical for lifelong hearing; however, mechanisms of structural homeostasis remain poorly understood. Conflicting models propose that stereocilia F-actin cores are either continually renewed every 24-48 h via a treadmill or are stable, exceptionally long-lived structures. Here to distinguish between these models, we perform an unbiased survey...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of theoretical biology
دوره 193 4 شماره
صفحات -
تاریخ انتشار 1998